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This relatively small GPCR family is characterized by a long extracellular ligand-binding domain stabilized by three disulfide bridges formed by six highly conserved cysteine residues, seven -helical transmembrane domains, universal for all GPCRs and an intracellular C-terminal domain, responsible mostly for receptor internalization due to the presence of multiple phosphorylation sites [22, 23]

Front Endocrinol (Lausanne) 14:1070592

Also, it is essential to implement longitudinal studies to assess the long-term effects of antioxidant use in the prevention and treatment of CAP, including potential benefits and risks as well as encourage comprehensive reporting of study results, including negative and inconclusive findings, to reduce publication bias and provide a more balanced view of the evidence

But then the patient gets sick, and then what do they do