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PMID: 33334899

In line with these findings, a mediation analysis revealed that increased DNA methylation of the principal adipogenic transcription factor GC1 gene locus in the placenta, responsible for glucose and lipid metabolism, was correlated with higher leptin levels in the cord blood of offspring exposed to maternal hyperglycemia in the second trimester [75]

Daily or twice-weekly dosing schedules would require much lower per-injection amounts and create unnecessary complexity for patients managing their weight loss journey

With so many opportunities the supplement industry can leverage, the sector is ripe for innovation and hungry for solutions for the 9% of Americans expected to be on GLP-1s by 2030.