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Unlike earlier GHRP compounds such as GHRP-6 and GHRP-2, ipamorelin exhibits a distinct selectivity profile: experimental studies have demonstrated that it does not release adrenocorticotropic hormone (ACTH) or cortisol at growth hormone-stimulating concentrations

This adaptive dormancy allows tumor cells to evade cytotoxic treatments and persist as minimal residual disease until conditions favor reactivation and relapse

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Genetics, diet, exercise, starting weight, metabolic health, and adherence all influence individual outcomes