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In this context, the functional mimicry of GLP-1 should be considered worthwhile if the designed agonist can act as a biased agonist of GLP-1R, selectively triggering anti-inflammatory signaling pathways that can aid in reducing the growth and differentiation of certain types of neuroendocrine tumors

Ethics declarations Competing interests We disclosed a patent related to this technology when this manuscript was submitted

The Semaglutide Patent Puzzle: Evergreening and the Uphill Battle for Indian Generics Post-2026 Semaglutide, Novo Nordisks blockbuster GLP-1 receptor agonist marketed as Ozempic and Wegovy, has revolutionized the management of type 2 diabetes and obesity