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Pallo, Kristine Faerch, Anette P

27 July 2011

Notably, these modifications do not act in isolation but are integrated within a broader network of post-translational modifications, amplifying the complexity of circadian control

While the passive technique focuses on drug and vehicle interaction and optimization to affect the stratum corneum structure, the active approach utilizes external energy to facilitate the transportation of drugs through the skin or by physically disrupting the outermost layer of the skin, known as the stratum corneum [230, 231]