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In general, the results on CSF amino acid levels in PD patients are inconclusive, because they might be influenced by selection of study subjects, sample size, lack of adequate matching between cases and controls in many studies, differences in antiparkinsonian therapy, and differences in study techniques, storage and handling of the samples (Jimnez-Jimnez et al., 1996

72 Use of mesenchymal stem cells is attractive as they can be manipulated into various lineages (muscle, bone, fat, cartilage, tendon, ligaments) thus being ideal candidates for use in the treatment of disc degeneration

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doi: 10.1155/2020/9010937 24 GaetaniLBoscaroFPieracciniGCalabresiPRomaniLDi FilippoMet al