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The transplanted human mesenchymal stem cells survived for at least six months and demonstrated expression of chondrocyte markers and mRNA expression of collagen IIA, IIB, versican, aggrecan, and Sox9 indicating differentiation into disc-like cells

Paraspinal muscle pathophysiology associated with low back pain and spine degenerative disorders

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Inadequate function of methionine synthase can lead to an accumulation of homocysteine, which has been associated with increased risk of cardiovascular disease and age-related neurodegenerative disease (e.g., Alzheimers disease)