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Discovery of the first lactate dehydrogenase proteolysis targeting chimera degrader for the treatment of pancreatic cancer

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550 g/mL) were tested on undifferentiated THP-1 cells, where no significant toxicity was observedno cytotoxicity, ROS induction, DNA, or oxidative damage

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Consistent with the known effects and common side effects of semaglutide, more participants receiving active medication reported decreased appetite as well as increased nausea and constipation

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Atg1-mediated Atg11 phosphorylation is required for selective autophagy by regulating its association with receptor proteins

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