Just as important, the trial results were produced under a prescription drug used as directed a research-use-only context is not the same setting, and the trial numbers cannot be assumed to transfer to it
132,133,134 Canonical Wnt signalling acts indirectly on -catenin to enhance its stability, allowing it to translocate from the cell surface to the nucleus, thereby linking extracellular signalling to nuclear gene expression regulation through downstream transcriptional machinery (Fig
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Therefore, based on summaries of the research regarding the relationship between breast cancer and GPxs, this article focused on the molecular mechanism and function of different GPxs and their diverse roles in the occurrence and development of breast cancer, further clarifying the pathogenesis of breast cancer and providing a potential direction for further studies on the treatment of breast cancers
