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In hepatocytes and adipocytes it reduces the activity of key lipogenic enzymes: Acetyl-CoA carboxylase (ACC) , a key step in fatty acid synthesis Fatty acid synthase (FAS) , the enzyme creating long chains of fatty acids Lipoprotein lipase (LPL) in adipocytes, reduces uptake of circulating triglycerides into fat cells Imagine it as turning valves in a pipeline, you close the inflow (lipogenesis), open the outflow (lipolysis)
6(1):30-9 Basic mechanisms involved in the anti-cancer effects of melatonin Mediavilla MD,et al Curr Med Chem 2010
Another drug, Liraglutide, has shown promise in preventing heroin cravings in rats
doi:10.1177/15563316251355551
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