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Our resulting model for downscaling, similar to fully convolutional models, can be trained on examples of smaller spatial domains (patches) and used at the evaluation stage on domains of arbitrary sizes, making it suitable for the generation of high-resolution data covering wider domains

LD50 values gained from monkeys indicated that 880 grams applied on the skin or 320 grams injected intravenously would result in 50% mortality in 80 kg humans 7

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