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Figure 3 3.3 Intestinal fat ferroptosis and IBD Studies have shown that high-fat diets (HFD) are associated with an increased risk of IBD, especially diets rich in cholesterol and animal fats, such as polyunsaturated omega-6 fatty acids (PUFA) and arachidonic acid (AA) (64)

LRRK2 mutations (e.g., G2019S) phosphorylate RAB GTPases, impairing autophagosome transport and causing immature autophagosome accumulation [154]

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Historically, private practice was the dominant model for physicians, offering them autonomy, flexibility, and the opportunity to build independent practices