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Int J Med Mushrooms 19(2):179189 Zheng H, Kim J, Liew M, Yan JK, Herrera O, Bok JW, Kelleher NL, Keller NP, Wang Y (2015) Redox metabolites signal polymicrobial biofilm development via the NapA oxidative stress cascade in Aspergillus

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Note that if youre interested in taking the prescription drug metformin for off-label use, you should consult with a doctor on the subject

2.2 ROS generation The lungs are especially vulnerable to oxidative stress compared to other organs due to their direct exposure to high oxygen levels (Cheresh et al., 2013)