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RahmanKVengrenyukYRamseySAVilaNRGirgisNMLiuJet alInflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression

Collectively, these findings link dietary lipotoxicity to incretin dysfunction in obesity and suggest that obesogenic diets impair GLP-1 signaling not only through excess caloric load but by directly disrupting the circadian architecture that governs hormone release

2026 Feb;13(10):e17825

In 39 randomized double-blind, placebo-controlled (RDP) human clinical trials including 2,009 subjects, Pycnogenol French maritime pine bark extract supplementation for two weeks to six months has been shown to beneficially affect cardiovascular health, chronic venous insufficiency, cognition, joint health, skin health, eye health, womens health, respiratory health and allergies, oral health and sports performance