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[7] Because it engages GIP and GLP-1 within one molecule, it is mechanistically distinct from CagriSema, which recruits amylin rather than GIP

Daniel Chille highlighted that the gut microbiome comprises over 50% of our cells and impacts multiple organs and immunity (32:23) He evaluates Firmicutes to Bacteroides ratios, secretory IgA levels, and mucosal barrier health to assess dysbiosis