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The glucagon receptor component adds a thermogenic element that neither semaglutide nor tirzepatide can match, directly increasing energy expenditure
For patients who struggle with emotional eating, phentermine or topiramate based therapies can help reduce impulsivity and cravings
Proper timing can help improve absorption and make both medications work better without interfering with each other
If these mechanisms translate consistently into humans, this could reshape how we think about patient selection and treatment goalsespecially in individuals who may not achieve substantial weight reduction but still derive meaningful hepatic benefit
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