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Specifically, the 12 mg arm of retatrutide has shown the highest discontinuation figures of the three compounds at their respective top doses, though investigators have suggested that part of the rate reflects participants who reached weight loss thresholds and chose to discontinue

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With CellTox Green Dye present, there was only a slight change in oxidized glutathione or total glutathione levels, indicating no adverse effect of multiplexing these two assays (compare green and gray bars, Figure 3, Panels B and C, Figure 4, Panel B and C)