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Compared with JAK and TYK2 inhibitors, which exert potent downstream modulation, compounds such as baicalin and EGCG exhibit only partial JAK/STAT or PDE-like immunomodulatory activity, and crucially, they lack human-grade PK/PD validation [36, 37]

[9] [10] Note: Standard multi-dose taurine vials contain benzyl alcohol as a preservative, and benzyl alcohol is contraindicated in neonates due to the risk of a potentially fatal gasping syndrome

Studies with these approaches have revealed improved inflammation resolution and recovery through glutathione reactive oxygen species (ROS) and glycating agent scavenging [57], which are downregulated after severe injury [64]

Association (single-sample GSEA enrichment) of lipid ontology classes with AML classified by differentiation visualized through a bubble plot