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While the licensed starting dose is 0.25 mg, prescribers commonly start patients switching from Mounjaro at higher doses

Phase 3 clinical trials testing GLP-1 RAs for weight management have demonstrated mean weight reduction of 8% to 15%, with 63% to 86% of patients achieving a 5% or greater reduction in body weight, and 33% to 69% achieving a 10% or greater reduction after 13 to 17 months of use

Endocrinol., 2021)

For example, acupuncture treatment may reduce abnormal intracellular calcium accumulation by stabilizing cell membranes, modulating impaired calcium channel function, or activating calcium pumps