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On the other hand, it may take some time to see the tangible fruits of your efforts

4.3 Related research in animal models In COPD animal models, research on ORs is still in its early stage

For example, in HGC-27 cells, lactylation of METTL16 at lysine 229 promotes cuproptosis via m 6 A modification of the mRNA of ferredoxin 1 (FDX1), a key factor encoding a reductase known to convert Cu 2+ to its more toxic form Cu 1+ , indicating the promising therapeutic potential of targeting Kla and cuproptosis in cancer