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H., Koh, B., Ndubuisi, M

NNMT is overexpressed in select tissues (e.g., adipose tissue, skeletal muscle, etc.) in pathophysiological conditions, making it a clinically relevant target for drug development in several chronic diseases including obesity and diabetes

The scientific rationale for peptide-based fat loss research centers on several key mechanisms: Lipolysis Activation: Peptides that increase cAMP in adipocytes (fat cells) activate hormone-sensitive lipase (HSL), which catalyzes the breakdown of stored triglycerides into free fatty acids a process called lipolysis