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Future studies will likely expand understanding of optimal applications and combination approaches for specific research goals

Step 03 two-stage Release phase 1 Initial research quantity released in stomach environment for upper-tract activity

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The ACO would participate under performance-based risk for the third and subsequent performance years of its second agreement period under the BASIC track, either by being automatically advanced to Level C, D and E for each of the 3 remaining performance years of its second agreement period under the glide path, or electing to advance more rapidly to higher levels of risk and reward along the glide path