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CoQ can either be reduced by mitochondrial DHODH or cytosolic FSP1 to produce CoQH2, a radical-trapping antioxidant with anti-ferroptosis activity

As implied by the terms, HFrEF represents HF where the left ventricular (LV) EF is markedly reduced (40% or lower), HFmrEF describes a mildly reduced LV EF of 40%49%, whereas in HFpEF the LV EF is preserved at around 50% or more

Beyond its role in energy metabolism, Acetyl L Carnitine Hydrochloride also acts as an antioxidant, helping to protect cells from oxidative stress

Additionally, it may be used in the management of angina, heart failure, and to improve exercise tolerance by enhancing energy production and reducing muscle fatigue