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If you inject into the exact same spot every time, the skin can become tough or lumpy, which may affect how the medication is absorbed

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Compared with untreated controls, microsomal protein concentrations were increased after twenty-eight days of treatment in C57BL mice, after four and twenty-eight days of treatment in C3H mice, after four days of treatment in B6C3F1 mice, and with no effect of treatment in C3B6F1 mice