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While most adverse effects observed have been manageable, certain patient profiles present a higher risk for complications and should be screened carefully before treatment initiation

Adipocyte Metabolism: Investigated for its ability to reduce white adipose tissue mass by shifting cellular metabolism away from storage and towards energy expenditure (without affecting food intake in murine models)

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Owing to such global re-establishment of methylation patterns, early pregnancy is thought to be particularly sensitive to adverse environmental influences, such as inadequate nutrition or stress, which have been correlated with increased emergence of anxiety, diabetes, obesity, and cancer in adulthood (Jirtle and Skinner, 2007)