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Potentially suicidal patients should not have access to large quantities of this drug

Semaglutide-treated rats ran for a greater distance and achieved higher exercise work compared to vehicle-treated rats ( Figure 1G and Figure S1D )

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The practical implication: if you are choosing between semaglutide and tirzepatide based solely on published trial outcomes (15% vs 20% weight loss), you are optimizing the wrong variable