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4,6 Many studies have shown the feasibility of NADs in disease prevention and treatment

Particularly noteworthy is that FOXO4 influences not only lifespan but also the quality of aging through its interaction with the protein p53commonly referred to as the "guardian of the genome." This interaction regulates whether cells remain in a senescent, metabolically inactive state or undergo programmed cell death (apoptosis)

Furthermore, chronic systemic inflammation induces a state of anabolic resistance within the muscle tissue

de La Puente-Yage M, Cuadrado-Cenzual MA, Ciudad-Cabaas MJ, Hernndez-Cabria M, Collado-Yurrita L