injection sites for b12 How To Give Injections At Home How to give a B12 shot correctly? How to Inject Vitamin B12

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In combined B12 and folate deficiency, B12 replacement must be started before folate supplementation to avoid precipitating or worsening neurological damage

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The difference is that leucovorin has been altered in a way that makes it easier to get through the blood-brain barrier for people who cant metabolize folic acid, he says