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Although, the induction of the Cdk1 mRNA expression was found relatively similar in both mice genotypes (Figure 5d), CDK1 protein, which is known to be expressed during DNA replication and progression in G2 and M phases, was transiently induced at 40 and 44 h in the WT livers while its expression increased progressively with maximal levels between 55 and 72 h in mutant mice (Figures 5b and c)

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The test identifies key genetic markers including GLP1R rs6923761 (GLP-1 receptor sensitivity), GIPR rs1800437 (dual-hormone response), FTO rs9939609 (baseline appetite regulation), and MC4R rs17782313 (satiety signaling)