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Recently, a drug targeting the receptors of both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) (tirzepatide) has been introduced to the market, and its indications have expanded to include treating obesity

For BrdU, cells on coverslips were incubated with 1 mol/L BrdU for 30 minutes

Simple nutrition and hydration measures substantially reduce side-effect burden: roughly 70% of patients report early nausea when starting semaglutide, and about 50% report fewer side effects after diet and fluid adjustments