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In fact, glutathione depletion is linked with a number of disease states and groups: Aging Athletic overtraining Major injuries and trauma Patients with wasting diseases such as HIV and AIDS Lung cancer Gut-based diseases such as Crohns and ulcerative colitis Chronic fatigue syndrome Alcoholism and fatty liver disease Diabetes and low glucose tolerance Cancer One of the most important things you can do to improve glutathione status is to remove or mitigate stressors that deplete glutathione

FEBS Letters, 1988

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According to official prescribing information, Wegovy can slow stomach emptying and affect how some oral medicines move through the stomach