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Moreover, liraglutide also displayed a boosted effect on levels of nitric oxide in mesenteric vessels and protection against endothelial dysfunction by increased production of plasminogen activator inhibitor type 1(PAI-1) and vascular adhesion molecule (VAM) (96)

295 SETDB1 has been shown to influence embryological development by promoting the maintenance of pluripotency and suppressing the differentiation of embryonic SCs, 296 and therefore, is required for nervous system development and function while dysregulation of SETDB1 is implicated in the pathogenesis of CNS disorders including ASD