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The approximately 380-hour half-life supports once-monthly dosing, which would be the longest dosing interval of any GLP-1 agonist

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Cook concluded: The fact that we have identified this potential population in the breast tissue thats regulated by most cancer therapies and that this population does have potential anticancer signaling [indicates] a conclusion that the breast has its own unique bacterial microbiome that can be modified by diet and drug administration and that it could represent a novel targetable factor to prevent breast cancer risk and reoccurrence. As a preclinical study, this work is subject to some limitations