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Phase 2 NEJM titration (still common in research) Phase 2 retatrutide titration schedule Phase Initiation Weeks Weeks 1-4 Weekly Dose 1 mg Phase Early escalation Weeks Weeks 5-8 Weekly Dose 2 mg Phase Mid escalation Weeks Weeks 9-12 Weekly Dose 4 mg Phase High escalation Weeks Weeks 13-16 Weekly Dose 8 mg Phase Maximum Weeks Weeks 17+ Weekly Dose 12 mg Source: Jastreboff et al., NEJM 2023

Supplied as a lyophilised 20mg blend, 99% purity by HPLC, Certificate of Analysis on request

Vitamin B12 itself is vital for energy production and maintaining healthy nerve cells, but its direct impact on weight loss needs to be clearly established

Patients in Arkansas, Louisiana, Mississippi, New Mexico, Kansas, Rhode Island, or West Virginia get a live video or audio visit instead, also included