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Se asocia con descensos del 82,4% de grasa heptica con normalizacin en el 86% con dosis semanal de 12mg en 24semanas, en relacin con la reduccin de tejido adiposo visceral, mejora de insulinosensibilidad, reduccin de leptina, aumento de adiponectina y evolucin favorable de parmetros del metabolismo lipdico y marcadores de fibrosis como Pro-C356