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thus, modulators of the Wnt/-catenin pathway have emerged to improve the efficacy of different immunotherapeutic agents in combination therapy, a finding that has already been researched in preclinical models

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Male C57BL/6 mice, aged 810 weeks and weighing between 20-28 g, were housed under controlled conditions (22C 2C, 12-hour light/dark cycle) and provided with ad libitum access to food and water