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Some flaking is normal during the first four weeks

Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated mean body weight reductions of up to approximately 24% over 48 weeks in adults with obesity a notable finding, though long-term durability data and head-to-head comparisons with other treatments are not yet available

These drugs can also cause bone marrow abnormalities, or may cause the platelet count to increase too much

Some peptides can be detected in specialized laboratory testing, namely: WORTH NOTING: Standard drug tests typically do not screen for peptides, as they are designed to detect common drugs like cannabis and opioids, requiring specialized testing for peptide detection