glutathione s transferase alpha S-transferase: A versatile and dynamic enzyme Overexpression of Glutathione S-Transferases in

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GFP signals within the inner autophagosome membrane are degraded in the autolysosomes but mRFP signals are relatively stable and thus provide a visible measure of autophagic flux status 33

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Mechanisms include reduction of excitotoxicity and oxidative stress, enhanced neurotrophic factor expression supporting neuronal survival, angiogenesis improving cerebral blood flow, and modulation of dopamine and serotonin systems