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The form of lipid peroxidation with the result of molecular oxygen conversion to reactive oxygen species (ROS) with various environmental factors, particularly cigarette smoke, alcohol, UV rays, and other oxidants, leads to oxidative stress

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Results Incubation with glutathione impairs hCC di-/oligomerization in cellular extracts and supernatants In our efforts to create a cell model and detection system for examining the effects of potential therapeutic agents on aggregation of L68Q-hCC, we created stable transfectants of HEK293T cells overexpressing and secreting either WT- or L68Q-hCC