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TLR4 expression is increased (1.9-fold) in the squamous epithelium of patients with RE compared to normal esophageal squamous epithelium (50)

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This transporter is well-characterized in terms of its structure and function, with a number of drugs decreasing thiamine transport through SLC19A3 (109)

It was initially hypothesized that following in vivo injection, MSCs contribute to tissue regeneration by migrating to the site of injury, engrafting, and differentiating into the appropriate cell type to replace damaged cells