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In the fully adjusted model ( Table 2 ) , IGF-1 serum concentrations were not associated with the risk of ALS neither in crude nor in fully adjusted models (top vs

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The results showed that RANKL induced osteoclast ferroptosis under normal oxygen condition, and the key mechanism was iron starvation response, which was manifested as decreased ferritin heavy chain (FTH), ferroportin (FPN) and increased TFR1