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For Research Use Only Not for Human or Veterinary Use This product is a research compound supplied exclusively for in-vitro laboratory research conducted by qualified researchers and institutions

Ethics The manuscript reporting studies did not involve human participants, human data, or human tissue

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This supports a model in which CHAC1-mediated GSH depletion destabilizes NRF2 and reduces cystine import, allowing iron-dependent lipid peroxides to accumulate and trigger ferroptosis