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Fourth, although our data represent a diverse population, findings may best apply to the USA and have more limited applicability to international settings

Bubbles in the vial do not indicate a problem

The newer GLP-1 medications like tirzepatide and semaglutide are generally more effective than traditional oral stimulant options, but their gastrointestinal side effects cause higher discontinuation rates (up to 6-7% in clinical trials versus 2-5% for older medications)

Additionally, the use of tirzepatide was linked to reductions in body weight, improved liver enzymes, and decreased intrahepatic fat content, hepatitis, and liver fibrosis as assessed noninvasively [10]