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Even though the brain appears to have plenty of GLP-1 receptors, GLP-1 seemingly cannot pass from the blood to access those receptors, says Stefan Trapp, PhD, a professor of autonomic neuroscience and metabolic disease at University College London

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These enzymes are mainly located in the liver but small quantities are present in lungs and kidney

In fact, the metabolic and cardiovascular benefits of sustained weight losssuch as improved glycaemic control, reduced blood pressure, and lower risk of obesity-related complicationsfar outweigh cosmetic concerns for most individuals