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And the data that existed back then wasnt very convincing

Furthermore, a prespecified subgroup analysis of HF individuals from the SELECT trial evaluating the effects of semaglutide on cardiovascular outcomes in people with overweight or obesity, which included 2,273 HFpEF and 1,347 HFrEF patients, showed that the therapy was associated with a reduction in the HF composite outcome (cardiovascular death or HF hospitalisation/emergency visit) across LVEF, suggesting that GLP-1 RAs may improve outcomes at least in obese HF patients regardless of diabetes status

They have to understand, 'Oh, crap, I do have gastroparesis

Where Real Timing Rules Do Exist There are timing instructions in the label that matter, and it is worth knowing which ones they are