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The analysis showed that, compared to the placebo, 73.3% of patients treated with the highest dose of tirzepatide achieved an absence of MASH with no worsening of fibrosis on liver histology compared to 13.2% of participants on placebo at 52 weeks of treatment , meeting the study's primary endpoint

B vitamins, particularly B12 and folate, play a role in producing brain chemicals that affect mood and other brain functions

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Theyre also approved for people with a BMI of 27 and at least one weight-related condition, like high blood pressure, high cholesterol, polycystic ovary syndrome (PCOS), or prediabetes