doi: 10.1186/s12951-018-0408-4 144 SinghDMohapatraPKumarSBeheraSDixitASahooSK
Furthermore, although substantial evidence supports an association between pathological hyperprolactinemia and adverse metabolic outcomes, recent studies have suggested that both excessively high and low prolactin levels may have adverse effects on metabolism
This is due to their efficacy in encapsulation, ability to traverse biological membranes, capacity for transporting lipophilic drugs, low cytotoxicity, and suitable size, as highlighted by research findings 15,16,17,18,19,20,21
Dapagliflozin alleviated cardiac diastolic and systolic dysfunction in the advanced progression of HFpEF by attenuating cardiac metabolic dysregulation through inhibiting myocardial fatty acid uptake and energy pathway activation [116]