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Rarely, hyperpigmentation of the hard palate has been observed, presumably related to drug intake [3, 18,19,20,21,22,23]

7.6 Hydration and Electrolytes GLP-1 therapy may reduce thirst perception in some individuals

adult obesity rate has dropped from a record 39.9% in 2022 to 37.0% in 2025 (a decline representing about 7.6 million fewer obese adults), a trend that aligns with a more than doubling in GLP-1 use for weight loss since early 2024