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The latest information about the proposed rule can be found on the Federal Register

Twelve RCTs were also excluded because they were conducted on children

Common Topamax side effects include: Nausea and diarrhea Dizziness, drowsiness, and trouble concentrating Numbness or tingling in the arms or legs Less common side effects that may be more severe include: Skin reactions, no matter how mild Vision problems, such as blurred vision Signs of kidney stones Symptoms of dehydration Allergic reaction Drinking alcohol with Topamax can lead to serious side effects like dehydration

BPC-157 addresses this connection at the cellular level