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Other related diseases such as fontal temporal dementia (FTD) appears to have overlap both with AD and ALS, and is commonly related with TDP-43 and C9ORF72 mutations of ALS (Warren et al., 2013), although there is evidence for TDP-43 involvement in AD, it appears to take a different progression pattern compared to ALS and FTD (Meneses et al., 2021), which suggests distinct disease mechanisms at play

Meloni, A., Pistoia, L., Positano, V., De Luca, A., Martini, N., Spasiano, A., et al

3 HGF/c-Met System Review AlzForum / Wright & Harding, Progress in Neurobiology (2015) This narrative review covers the development of small-molecule angiotensin IV analogues for Alzheimers and Parkinsons diseases, with Dihexa as the lead candidate at the time of writing

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